← science

pressure & light

Different physics, converging biology. One pushes oxygen into plasma under pressure. The other moves photons through tissue. They meet in the mitochondria.

hbot deep dive nir deep dive
HBOT NIR shared pathways Dissolved plasma O₂ Henry's Law Stem cell mobilization eNOS / MMP-9 Telomere lengthening Efrati 2020 Senescent cell clearance Efrati 2020 Erythropoiesis EPO upregulation Edema reduction hyperoxic vasoconstriction Cytochrome c oxidase photoacceptor Direct ATP enhancement Complex IV electron flow Nitric oxide release photodissociation from CCO Collagen synthesis fibroblast stimulation Transcranial delivery 810nm penetrates skull ROS signaling hormesis NF-κB suppression anti-inflammation Angiogenesis VEGF upregulation HIF-1α activation different triggers, same target M1→M2 polarization macrophage repair shift Neuroplasticity different routes, same outcome Mitochondrial biogenesis new mitochondria growth

Two modalities, different physics, converging biology.
This is why we use both.